Speckle tracking echocardiography: clinical applications in cardiac resynchronization therapy.

Comparison of CMR DENSE strain imaging and 2D speckle tracking echocardiography for cardiac resynchronization therapy (CRT) response

Background Considering that nonresponse rates to cardiac resynchronization therapy (CRT) are typically 35-50%, assessment of the cardiac substrate for CRT with cardiac imaging could be very helpful for many patients with heart failure referred for this therapy. We have previously shown that CMR assessment of dyssynchrony using displacement encoding with stimulated echoes (DENSE) is strongly ass...

Echocardiography-Guided Left Ventricular Lead Placement for Cardiac Resynchronization Therapy: Results of the Speckle Tracking Assisted Resynchronization Therapy for Electrode Region (STARTER) Trial Saba et al: Echo-Guided LV Lead Placement in CRT

Dyssynchrony by speckle-tracking echocardiography and response to cardiac resynchronization therapy: results of the Speckle Tracking and Resynchronization (STAR) study

AIMS The Speckle Tracking and Resynchronization (STAR) study used a prospective multi-centre design to test the hypothesis that speckle-tracking echocardiography can predict response to cardiac resynchronization therapy (CRT). METHODS AND RESULTS We studied 132 consecutive CRT patients with class III and IV heart failure, ejection fraction (EF) < or =35%, and QRS > or =120 ms from three inter...

Echocardiography-guided left ventricular lead placement for cardiac resynchronization therapy: results of the Speckle Tracking Assisted Resynchronization Therapy for Electrode Region trial.

BACKGROUND Cardiac resynchronization therapy improves mortality and morbidity in patients with heart failure (HF) with wide QRS complex and diminished left ventricular (LV) function, but response is variable. METHODS AND RESULTS The Speckle Tracking Assisted Resynchronization Therapy for Electrode Region (STARTER) was a prospective, double-blind, randomized controlled trial testing the hypoth...

Strain dyssynchrony index determined by three-dimensional speckle area tracking can predict response to cardiac resynchronization therapy

BACKGROUND We have previously reported strain dyssynchrony index assessed by two-dimensional speckle tracking strain, and a marker of both dyssynchrony and residual myocardial contractility, can predict response to cardiac resynchronization therapy (CRT). A newly developed three-dimensional (3-D) speckle tracking system can quantify endocardial area change ratio (area strain), which coupled wit...